In patients with normal LFTs at baseline, bilirubin values greater than the ULN occurred in % of patients. Increases in AST or ALT > times the ULN, or alkaline phosphatase > times ULN, were observed in % and % of patients, respectively. While on TAXOTERE, increases in AST and/or ALT > times ULN concomitant with alkaline phosphatase > times ULN occurred in % of patients with normal LFTs at baseline. Whether these changes were related to the drug or underlying disease has not been established.
Joseph Bennington-Castro is a Hawaii-based contributing writer for Live Science and . He holds a master's degree in science journalism from New York University, and a bachelor's degree in physics from the University of Hawaii. His work covers all areas of science, from the quirky mating behaviors of different animals, to the drug and alcohol habits of ancient cultures, to new advances in solar cell technology. On a more personal note, Joseph has had a near-obsession with video games for as long as he can remember, and is probably playing a game at this very moment.