Ketosteroid levels

Gynecomastia is a common adverse effect of bicalutamide (Casodex) therapy that may prompt some men to discontinue prostate cancer treatment. Tamoxifen has been recommended as a preventive agent for gynecomastia in these patients. A double-blind study of 282 men randomized to receive 20 mg of tamoxifen once per day with bicalutamide or bicalutamide alone found that after six months, gynecomastia and breast pain were significantly reduced in men who received tamoxifen ( versus percent in the control group). 41 An Italian randomized controlled trial of 80 participants also found that 20 mg of tamoxifen once per week is as effective as 20 mg once per day. 42

Pregnancy Category C. MINIPRESS has been shown to be associated with decreased litter size at birth, 1, 4, and 21 days of age in rats when given doses more than 225 times the usual maximum recommended human dose. No evidence of drug-related external, visceral , or skeletal fetal abnormalities were observed. No drug-related external, visceral, or skeletal abnormalities were observed in fetuses of pregnant rabbits and pregnant monkeys at doses more than 225 times and 12 times the usual maximum recommended human dose, respectively.

Your evidence is anecdotal therefore irrelevant. I am however very happy that your mum is doing well. Now eGFR fluctuates for a number of reasons, and without proper empirical evidence, none of it can be explained. The most reasonable assumption is that she was suffering from an acute episode of a chronic condition. That is the kidneys got worse for a short term, usually due to an infection but also be dehydration. After that the kidneys returned to a baseline which is still stage 4 CKD but not as bad as Stage 5. Lastly I do know what I am talking about and I would appreciate if you treat me with respect and not be so rude in future.

Standardized rhodiola supplements have also been put to the test in physicians during two-week stretches on night duty and in students during final exams. These trials have confirmed the herb’s general anti-fatigue effect, showing that it improves tests of physical fitness, mental fatigue and neuromotor function under stress.
Many people who have tried rhodiolareport that they feel better while taking it. The experience is described in terms of a continuous sensation of physical and mental relief from stress, and anecdotally the effect appears to be most pronounced in people who typically respond to stress with anger or feelings of helplessness. Animal studies on rhodiola have given us some clues as to the neurochemical basis of these effects, such as its effects on the metabolism of the serotoninergic system, boosting brain levels of dopamine, acetylcholine, and norepinephrine. The evidence also seems to suggest that rhodiola  influences the synthesis, levels, and/or activity of endorphins and enkephalins, since blocking the receptors for some of these “feel-good” peptides negates some of  its effects.

Ketosteroid levels

ketosteroid levels

Standardized rhodiola supplements have also been put to the test in physicians during two-week stretches on night duty and in students during final exams. These trials have confirmed the herb’s general anti-fatigue effect, showing that it improves tests of physical fitness, mental fatigue and neuromotor function under stress.
Many people who have tried rhodiolareport that they feel better while taking it. The experience is described in terms of a continuous sensation of physical and mental relief from stress, and anecdotally the effect appears to be most pronounced in people who typically respond to stress with anger or feelings of helplessness. Animal studies on rhodiola have given us some clues as to the neurochemical basis of these effects, such as its effects on the metabolism of the serotoninergic system, boosting brain levels of dopamine, acetylcholine, and norepinephrine. The evidence also seems to suggest that rhodiola  influences the synthesis, levels, and/or activity of endorphins and enkephalins, since blocking the receptors for some of these “feel-good” peptides negates some of  its effects.

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